The population growth of Tanah Bumbu Regency is among the highest in South Kalimantan Province. The annual population growth rate for 2023–2024 was recorded at 1.55 percent.

According to data from the Central Statistics Agency (BPS), the population of Tanah Bumbu Regency in 2024 reached 346,336 people, with a Sex Ratio of 105.46. The male population is 2.66 percent higher than the female population.